How many doses are required for the rabies vaccine booster?

Rabies vaccine booster shots generally require two doses.

The rabies vaccine is produced by inoculating attenuated rabies virus fixed strains into suitable culture media, followed by a series of manufacturing processes including viral amplification, harvesting, inactivation, concentration, and purification. It is used to prevent rabies. Rabies vaccine boosting refers to individuals who have previously received rabies prophylaxis, either pre-exposure or post-exposure prophylaxis. Veterinarians, rabies virus researchers, and wilderness explorers often receive vaccination in advance as pre-exposure prevention.

If bitten or scratched by cats or dogs, individuals receiving the rabies vaccine for the first time should, after timely and proper wound management, complete a full course of five vaccine doses as directed by a physician. If bitten or scratched again by animals such as cats or dogs, in addition to immediate and proper wound washing and disinfection, two booster doses are required—one on day 0 and another on day 3—to enhance immunity. Furthermore, individuals who have received pre-exposure prophylactic vaccination should have their blood-specific antibody levels monitored every two years. If antibody titers decline, a single booster dose should be administered to increase antibody levels and ensure effective protection.

To ensure safety, individuals bitten by animals should follow professional medical advice regarding rabies vaccine administration.