Can I get a COVID-19 booster shot two weeks after having a breast biopsy?

Dec 10, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
Half a month after a breast biopsy, if the wound has healed well and there is no discomfort, it is acceptable to receive a COVID-19 booster shot. However, if the biopsy site has not fully healed and still shows signs of redness, swelling, bleeding, or infection, or if you have symptoms such as cold or fever, vaccination may worsen local reactions and increase bodily stress, potentially affecting the vaccine's immune response. In such cases, vaccination should be postponed until the wound has completely healed and your health has fully recovered.

Under normal circumstances, if the breast biopsy wound has healed well and there are no discomfort symptoms half a month after the procedure, it is acceptable to receive a COVID-19 booster shot. However, if there are signs of wound abnormalities or physical discomfort, vaccination should be postponed. If in doubt, it is recommended to consult a healthcare provider in advance. Detailed analysis is as follows:

If the biopsy wound has fully healed without any abnormalities such as redness, swelling, pain, or discharge, and there are no systemic symptoms like fever or fatigue, immunity is likely restored. In this case, receiving a COVID-19 booster will not interfere with wound healing and can effectively trigger the expected immune response.

However, if the biopsy wound remains unhealed, with signs of redness, swelling, bleeding, or infection, or if the individual is experiencing cold-like symptoms or fever, vaccination may exacerbate local reactions and overall physical stress, and could potentially impair the vaccine's immunogenicity. In such cases, vaccination should be delayed until the wound has completely healed and the body has fully recovered.

Prior to vaccination, individuals must inform the healthcare provider about their recent biopsy history so that the provider can assess whether they meet the criteria for vaccination. After vaccination, individuals should remain under observation for the required period, maintain cleanliness at the injection site, and seek medical attention promptly if persistent adverse symptoms occur.