What does elevated PO2 indicate?

Elevated PO2 refers to a significant increase in red blood cell count, hemoglobin concentration, and hematocrit in a unit volume of blood compared to reference values.

PO2 stands for partial pressure of oxygen, with a normal reference range of 95–100 mmHg. The level of PO2 is closely related to blood oxygen saturation, showing a positive correlation. Oxygen saturation refers to the proportion of hemoglobin bound to oxygen relative to all hemoglobin capable of binding oxygen. Low PO2 can lead to insufficient blood oxygen saturation, causing symptoms such as dizziness, cyanosis of the lips, and increased heart rate.

Elevated PO2 is mainly associated with respiratory acidosis and metabolic alkalosis. In cases of respiratory acidosis, continuous low-concentration oxygen therapy is recommended, typically with an oxygen concentration below 35%. Long-term low-dose oxygen therapy reduces pulmonary circulation resistance, lowers pulmonary arterial pressure, and promotes carbon dioxide elimination. Mechanical ventilation increases overall ventilation capacity and effectively removes CO2; by adjusting relevant parameters, it enhances ventilation and efficiently expels carbon dioxide. For patients with metabolic alkalosis, potassium chloride may be administered intravenously or orally under medical supervision to promote renal excretion of bicarbonate and reduce carbon dioxide levels in the body.

Patients should ensure adequate rest and avoid excessive fatigue in daily life.