Causes of enlarged axillary lymph nodes in women

Feb 24, 2023 Source: Cainiu Health
Dr. Sun Shaolong
Introduction
Enlarged axillary lymph nodes in women are associated with breast-related diseases, such as mastitis or breast tumors, and may also be caused by lymphoma. Patients with mastitis often present obvious systemic symptoms, such as chills, high fever, and increased pulse rate, which can lead to reactive hyperplasia and enlargement of the axillary lymph nodes. In addition, tuberculous lymphadenitis can also cause enlarged axillary lymph nodes in women.

Swollen lymph nodes in the female axilla are often associated with breast-related diseases, such as mastitis or breast tumors, and may also be caused by lymphoma.

1. Mastitis

Mastitis refers to a purulent infection of the breast tissue, which commonly occurs within three weeks postpartum. Because the breast has abundant blood vessels and good circulation, patients often develop prominent systemic symptoms early on, including chills, high fever, and rapid pulse. Reactive enlargement of the axillary lymph nodes is frequently observed. It is generally recommended that patients seek prompt medical attention when symptoms appear. Under a doctor's guidance, broad-spectrum antibiotics such as penicillin, erythromycin, or cephalosporins can be used for anti-infective treatment.

2. Breast Tumor

Metastasis of breast tumors to ipsilateral axillary lymph nodes is common. The enlarged lymph nodes are typically hard, painless, and may progressively coalesce into masses. As the disease advances, they may adhere to the skin or deep tissues and become immobile. The primary management approach for this condition is surgical treatment. A comprehensive, multidisciplinary strategy guided by physicians may include radical or palliative surgery, followed by chemotherapy, radiotherapy, endocrine therapy, or targeted therapy. Current treatment trends emphasize individualized, integrated approaches.

3. Lymphoma

Patients with lymphoma may experience chest tightness, chest pain, and progressive enlargement of axillary lymph nodes. Chemotherapy under medical supervision is required.

In addition, tuberculous lymphadenitis can also cause swollen axillary lymph nodes in women. It is advisable to seek immediate medical evaluation upon symptom onset to rule out the risk of malignancy.

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