4mm ground-glass nodule malignancy rate
Ground-glass nodules usually refer to pulmonary ground-glass nodules. The malignancy rate of a 4mm pulmonary ground-glass nodule is generally no more than 10%.
Pulmonary ground-glass nodules may be caused by inflammatory lesions or early malignant changes. Typically, the smaller the nodule size, the lower the risk of malignancy. A 4mm pulmonary ground-glass nodule is clinically considered a very small lung nodule, often benign, with slow growth and patterns such as lepidic or atypical adenomatous hyperplasia. The risk of malignant transformation is relatively low, usually not exceeding 10%. Regular follow-up observation is recommended to determine whether there are significant changes in the nodule.
If the ground-glass nodule is found to increase rapidly in size, or if chest CT reveals signs such as pleural retraction, spiculation, or lobulation, these may indicate potential malignancy. In such cases, a biopsy may be recommended by a physician to determine the nature of the nodule (benign or malignant), and appropriate treatment can be selected under medical guidance based on the biopsy results.