Can I take a nucleic acid test 24 or 48 hours after vaccination?
Feb 27, 2023
Source: Cainiu Health
Dr. Guo Xiheng
Introduction
Nucleic acid testing usually refers to nucleic acid detection. If you receive live-attenuated vaccines or subunit vaccines, they generally do not affect the results of nucleic acid testing, so vaccination can be done at any time. However, if you receive inactivated vaccines, it is generally recommended to wait at least 48 hours between vaccination and testing, because after 48 hours, complete viral fragments in the body have typically been metabolized and are unlikely to interfere with nucleic acid test results, thereby improving the accuracy of testing.
Nucleic acid testing usually refers to nucleic acid detection. Whether one can undergo nucleic acid testing 24 or 48 hours after vaccination generally depends on the type of vaccine received.
In clinical practice, there are various types of vaccines. If a live attenuated vaccine or subunit vaccine is administered, since these vaccines do not contain viral nucleic acid sequences, they typically do not affect nucleic acid test results. Therefore, nucleic acid testing can be performed at any time after receiving such vaccines.
However, if an inactivated vaccine is administered, which contains pathogen nucleic acid sequences, undergoing nucleic acid testing immediately after vaccination may interfere with the test results and lead to false-positive outcomes. It is generally recommended to wait at least 48 hours. By this time, any complete viral fragments present in the body have usually been metabolized and eliminated, minimizing interference with the test and improving the accuracy of the nucleic acid test results.
