What bacteria cause pyelonephritis?

Feb 28, 2023 Source: Cainiu Health
Dr. Zhao Xinju
Introduction
Pyelonephritis may be caused by Escherichia coli, alpha-hemolytic streptococcus, Klebsiella, Citrobacter, Streptococcus pneumoniae, etc. In addition, Staphylococcus aureus and Pseudomonas aeruginosa can also potentially cause pyelonephritis. If pyelonephritis occurs, patients may take medications such as cefixime capsules or minocycline hydrochloride capsules under the guidance of a physician.

Generally, pyelonephritis may be caused by Escherichia coli, alpha-hemolytic streptococcus, Klebsiella, Citrobacter, Streptococcus pneumoniae, and other pathogens. The specific analysis is as follows:

1. Escherichia coli

Some patients with pyelonephritis may develop the condition due to infection by Escherichia coli. This is because E. coli has fimbriae that enable it to adhere to the ureteral wall, potentially leading to pyelonephritis.

2. Alpha-hemolytic streptococcus

Alpha-hemolytic streptococcus, also known as group A hemolytic streptococcus or viridans streptococcus, may cause acute pyelonephritis. The bacteria can gradually ascend into the renal pelvis, resulting in infection.

3. Klebsiella

Klebsiella is a Gram-negative bacterium commonly found in the human intestinal tract and urinary tract. When this bacterium enters the urethra and multiplies in urine, it may travel further through the urinary tract into the bladder and renal pelvis, causing infection. Therefore, Klebsiella is one of the common pathogens responsible for urinary tract infections, including pyelonephritis.

4. Citrobacter

Citrobacter is another microorganism classified as a Gram-negative bacillus. It is widely present in natural environments such as soil and water. Although Citrobacter is typically a normal component of the intestinal flora, under certain conditions it can cause urinary tract infections, including pyelonephritis. This may occur due to the bacterial characteristics and pathogenic mechanisms of Citrobacter after it enters the urinary tract.

5. Streptococcus pneumoniae

In certain circumstances—such as in individuals with compromised immune function or structural abnormalities in the urinary tract—Streptococcus pneumoniae may enter the urinary system via ascending infection from the lower respiratory tract. In such cases, the bacteria can enter the urethra and bladder, subsequently infecting the renal pelvis and causing pyelonephritis.

In addition, other bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa may also lead to pyelonephritis. If pyelonephritis occurs, patients can take medications such as cefixime capsules or minocycline hydrochloride capsules under medical guidance. Meanwhile, during treatment, patients should maintain good personal hygiene and drink plenty of water.


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