What is the most common pathogen causing pyelonephritis?

Sep 15, 2023 Source: Cainiu Health

Dr. Yang Ziqi

Introduction

Generally speaking, there is no single most common causative agent of pyelonephritis. Common pathogens causing pyelonephritis include Escherichia coli, Klebsiella pneumoniae, Proteus species, Citrobacter species, and Pseudomonas aeruginosa. Escherichia coli is a Gram-negative bacterium normally found in the intestines, which can ascend through the urethra to the bladder, ureters, and kidneys, causing infection.

Generally speaking, there is no single most common causative bacterium for pyelonephritis. Common pathogens responsible for pyelonephritis include Escherichia coli, Klebsiella pneumoniae, Proteus species, Citrobacter species, and Pseudomonas aeruginosa. Detailed analysis is as follows:

1. Escherichia coli

Escherichia coli is a Gram-negative bacterium normally found in the intestinal tract. It can ascend through the urethra to the bladder, ureters, and kidneys, causing infection.

2. Klebsiella pneumoniae

Klebsiella pneumoniae is a member of the Enterobacteriaceae family and is a major pathogen in respiratory infections. It exhibits resistance to many antibiotics and commonly causes severe pneumonia. It can also lead to urinary tract infections, nephritis, sepsis, and suppurative meningitis.

3. Proteus species

Proteus bacteria are highly motile and pleomorphic intestinal bacteria characterized by active movement, presence of flagella, lack of capsule and spores, and Gram-negative staining.

4. Citrobacter species

Citrobacter is a Gram-negative rod belonging to the normal intestinal flora. It is an opportunistic pathogen that may proliferate abnormally and become more virulent under certain conditions, leading to infections such as meningitis, prostatitis, and vaginitis.

5. Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic pathogen that can infect both humans and plants. Infections caused by this bacterium often produce green-colored pus and exudates.

If patients experience any discomfort or symptoms, it is recommended to seek timely medical attention at a hospital to avoid delays in diagnosis and treatment.

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