What to do if female sex hormone-binding globulin is low

Mar 28, 2023 Source: Cainiu Health

Dr. Zhao Xiaodong

Introduction

Low levels of sex hormone-binding globulin (SHBG) in women may be caused by endocrine disorders, hypothyroidism, polycystic ovary syndrome (PCOS), or other reasons. It is recommended to undergo timely examinations for accurate diagnosis and, under medical guidance, improve the condition through lifestyle modifications, medication, and other treatments. In addition to the above causes, it may also be associated with conditions such as diabetes.

Low levels of sex hormone-binding globulin in women may be caused by endocrine disorders, hypothyroidism, polycystic ovary syndrome (PCOS), or other reasons. It is recommended to undergo timely medical evaluation for an accurate diagnosis and, under a doctor's guidance, improve the condition through lifestyle adjustments, medication, and other treatments.

1. Endocrine Disorders

If women frequently experience excessive fatigue or high mental stress, it may lead to endocrine imbalance and abnormal hormone secretion. Adjusting lifestyle habits appropriately and maintaining a positive mindset can help improve symptoms.

2. Hypothyroidism

Hypothyroidism can affect ovarian secretion, leading to reduced testosterone levels and consequently decreased sex hormone-binding globulin. Under medical guidance, timely iodine supplementation is recommended, including consuming more iodine-rich foods such as seaweed and kelp.

3. Polycystic Ovary Syndrome (PCOS)

This condition causes increased secretion of androgens, which may impair estrogen synthesis and result in low sex hormone-binding globulin levels. Under a doctor’s supervision, medications such as progesterone soft capsules, medroxyprogesterone acetate tablets, and clomiphene citrate tablets may be used. In severe cases, bilateral oophorectomy or laparoscopic ovarian drilling may be required as advised by a physician to manage the condition.

In addition to the above causes, low sex hormone-binding globulin may also be associated with conditions such as diabetes.

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