Hepatitis B 135 positive (large three positives), liver function normal, is the infectivity high?
Mar 28, 2023
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
A person with positive results for hepatitis B surface antigen, hepatitis B e-antigen, and hepatitis B core antibody, but with normal liver function, is considered a hepatitis B virus carrier. Generally, no specific treatment is required; regular follow-up examinations at the hospital are sufficient. However, the level of infectivity is not directly related to liver function, but primarily depends on the hepatitis B viral load measurement.
In general, "HBsAg, HBeAg, and anti-HBc positive" (commonly known as the "big three positives") refers to a condition in which hepatitis B surface antigen, hepatitis B e-antigen, and hepatitis B core antibody are all positive. Even if liver function is normal, the infectivity is generally high. The detailed analysis is as follows:
When hepatitis B surface antigen, hepatitis B e-antigen, and hepatitis B core antibody are all positive but liver function remains normal, this indicates that the individual is a hepatitis B virus carrier. Usually, no specific treatment is required; regular follow-up examinations at the hospital are sufficient. However, the level of infectivity is not directly related to liver function, but primarily depends on the amount of hepatitis B virus present. At this stage, the viral load in the patient's body is relatively high, resulting in strong infectivity. The virus can be transmitted through blood, sexual contact, mother-to-child transmission, and other routes. Therefore, appropriate preventive measures should be taken, including timely vaccination, to avoid infection.
It is also important to develop healthy lifestyle habits, wear masks when going out, and avoid sharing personal items with others.
