Is a positive antiglobulin test serious?
Apr 15, 2023
Source: Cainiu Health
Dr. Guo Xiheng
Introduction
A positive antiglobulin test, if caused by autoimmune hemolytic anemia, is generally not severe. However, if it is associated with rheumatoid arthritis, the condition is more serious and prompt medical treatment at a hospital is recommended, which usually allows good control of the disease. A positive antiglobulin test may also result from lymphoma, which is likewise a serious condition requiring timely hospital treatment.
If the antiglobulin test is positive due to autoimmune hemolytic anemia, the condition is generally not serious. However, if it is caused by rheumatoid arthritis, the situation is more severe, and prompt medical treatment at a hospital is recommended, which can usually effectively control the disease. Specific analysis is as follows:
1. Not serious
The antiglobulin test is a method used to detect whether there are autoantibodies present in the body, and includes both direct and indirect tests. A positive antiglobulin test indicates the presence of autoantibodies on the red blood cell membrane, most commonly due to autoimmune hemolytic anemia. This condition is generally not severe. Under a doctor's guidance, medications such as prednisolone tablets or dexamethasone tablets may be used, and the prognosis is typically favorable.
2. Serious
A positive antiglobulin test may also result from rheumatoid arthritis, in which patients often experience recurrent, multiple small-joint inflammations. This condition poses significant harm to the body and is considered serious. Under medical supervision, drugs such as ibuprofen sustained-release capsules or indomethacin tablets may be prescribed. However, the prognosis is generally poor, and treatment mainly aims to control disease progression.
In addition, a positive antiglobulin test could also be caused by lymphoma, which is another serious condition. Timely hospital evaluation and appropriate treatment under a doctor’s guidance are necessary.
