What are the effects of elevated D-dimer levels in late pregnancy on pregnant women?

May 10, 2023 Source: Cainiu Health

Dr. Lv Aiming

Introduction

In late pregnancy, elevated D-dimer levels in pregnant women may typically lead to narrowed or blocked blood vessels, causing symptoms such as dizziness and nausea. They may also affect normal blood circulation, increasing the risk of venous thrombosis and excessive bleeding during delivery. Additionally, due to increased coagulation function, there is a higher risk of developing hypertensive disorders of pregnancy.

Elevated D-dimer levels in late pregnancy typically affect pregnant women by impairing normal coagulation function, promoting venous thrombosis, and increasing the risk of hypertensive disorders of pregnancy. The specific analysis is as follows:

1. Impairment of normal coagulation function

In clinical practice, D-dimer is primarily used for diagnosing venous thromboembolism, deep vein thrombosis, and pulmonary embolism. Elevated D-dimer levels in late pregnancy usually indicate a hypercoagulable state in the expectant mother. Due to increased blood viscosity, this may lead to vascular narrowing or occlusion, resulting in symptoms such as dizziness and nausea.

2. Venous thrombosis formation

Elevated D-dimer levels during late pregnancy may also disrupt normal blood circulation, increasing the risk of venous thrombosis, which could lead to severe hemorrhage during delivery.

3. Hypertensive disorders of pregnancy

An increased level of pro-coagulant factors in the blood, along with reduced anticoagulants and fibrinolytic activity, enhances coagulation function and may contribute to the development of hypertensive disorders during pregnancy.

In addition, elevated D-dimer levels may also lead to disseminated intravascular coagulation (DIC), placental infarction, preterm birth, and other complications. It is recommended that pregnant women follow medical advice for regular prenatal checkups, maintain healthy lifestyle habits, and ensure both maternal health and normal fetal development.

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