Which medications are prone to cause orthostatic hypotension?
May 11, 2023
Source: Cainiu Health
Dr. Tian Hongbo
Introduction
In general, medications such as diuretics, nitrates, and α-receptor antagonists are prone to cause orthostatic hypotension. In addition to these commonly used drugs, others—including antidepressants, calcium channel blockers, and phosphodiesterase inhibitors—may also lead to this condition. If any discomfort symptoms occur, it is recommended to seek timely medical attention to avoid delaying the illness.
Diuretics, nitrates, alpha receptor antagonists, and other medications commonly cause orthostatic hypotension. Specific details are as follows:
1. Diuretics
Medications such as furosemide tablets and hydrochlorothiazide tablets reduce blood pressure by decreasing extracellular fluid volume. During treatment, when a person stands up suddenly, orthostatic hypotension may occur due to low blood volume.
2. Nitrates
Drugs such as nitroglycerin tablets and isosorbide dinitrate tablets primarily lower blood pressure by dilating blood vessels, leading to a temporary reduction in effective blood volume, which may trigger orthostatic hypotension.
3. Alpha Receptor Antagonists
Medications such as phentolamine mesylate tablets and terazosin hydrochloride tablets may impair neurovascular reflex regulation and lead to decreased blood pressure, resulting in orthostatic hypotension.
In addition to the above commonly used drugs, others such as antidepressants, calcium channel blockers, and phosphodiesterase inhibitors may also contribute. If any discomfort symptoms occur, it is recommended to seek timely medical attention to avoid delaying diagnosis and treatment.
