What does immunohistochemistry and molecular testing mean?
May 14, 2023
Source: Cainiu Health
Dr. Qi Zhirong
Introduction
Immunohistochemistry can determine the nature and subtype of malignant tumors, while molecular testing helps doctors make accurate diagnoses and obtain more precise pathological classifications, thereby facilitating targeted treatment of malignancies. Overall, both immunohistochemistry and molecular testing are important tools that assist physicians in tumor identification and treatment decision-making by detecting specific markers in tumor cells.
In general, immunohistochemistry can determine the nature and subtype of malignant tumors, while molecular testing helps doctors make accurate diagnoses and obtain more precise pathological classifications, thereby facilitating targeted treatment of malignant tumors. Specific analyses are as follows:
1. Immunohistochemistry
Immunohistochemistry is a technique that identifies tumor types by detecting protein expression in tissue sections. Specifically, it uses specific antibodies to bind target proteins through immune reactions, and visualizes protein expression in specimens via chromogenic methods, thus helping physicians determine tumor type and grade.
2. Molecular Testing
Molecular testing is a method used to detect specific genetic mutations or abnormal gene expression in tumor cells. These genetic alterations or expression abnormalities may influence tumor growth, metastasis, and response to drug therapies. By performing molecular testing, doctors can understand the genetic profile of the tumor and select more personalized and precise treatment strategies.
Overall, both immunohistochemistry and molecular testing are essential tools for identifying tumors and guiding treatment decisions by detecting specific biomarkers in tumor cells.
