What is immunohistochemistry used for?
May 14, 2023
Source: Cainiu Health
Dr. Qi Zhirong
Introduction
Immunohistochemistry is a method used to detect the expression of specific proteins in biological samples, commonly applied in pathology and biomedical research. By using specific antibodies, it identifies particular proteins in tissue sections or cells, thereby determining the type and quantity of proteins present in tissues or cells. It is widely used in identifying cancer types, assessing cancer grading and staging, and predicting treatment response.
Generally, immunohistochemistry is a method used to detect the expression of specific proteins in biological samples, commonly employed in pathology and biomedical research. The detailed analysis is as follows:
This technique uses specific antibodies to identify particular proteins in tissue sections or cells, thereby determining the type and quantity of proteins present in tissues or cells. In cancer research and diagnosis, immunohistochemistry is widely applied to identify cancer types, assess tumor grading and staging, and predict treatment response.
In immunohistochemistry, specific antibodies are labeled with dyes or fluorophores, which bind to antigens in the sample to form specific complexes. These complexes are then detected and quantified using staining or fluorescence visualization methods. This method is frequently used in pathological diagnosis, enabling the detection of specific proteins or antigens within cells or tissues to help determine the type and severity of disease.
