How high is too high for cystatin C to be considered severe?
May 15, 2023
Source: Cainiu Health
Dr. Yang Shuwen
Introduction
Cystatin C is a type of cysteine protease inhibitor primarily produced by the kidneys and is clinically used to assess kidney function. In most cases, elevated levels of cystatin C indicate kidney damage. Normally, if cystatin C levels exceed the normal range by 1.5 to 2 times, it suggests the presence of mild renal impairment.
Under normal circumstances, the reference range for cystatin C is 0.5–1.1 mg/L. If the level exceeds the normal range by 1.5 to 2 times, it indicates a relatively serious condition. Detailed analysis is as follows:
Cystatin C is a type of cysteine protease inhibitor primarily produced by the kidneys and is clinically used to evaluate kidney function. In most cases, elevated cystatin C levels indicate kidney damage. When cystatin C exceeds the normal range by 1.5 to 2 times, it suggests mild renal impairment, which constitutes a relatively severe situation. Without active cooperation with medical treatment, this may lead to renal insufficiency or even kidney necrosis.
Although cystatin C can be used to assess kidney injury, relying solely on cystatin C is insufficient for a comprehensive evaluation of disease severity. When necessary, additional assessments such as glomerular filtration rate (GFR) and imaging studies should be performed in consultation with a physician to accurately determine the extent of kidney damage. It is important to clearly understand the specific progression of the disease and follow medical advice for standardized management.
