What is the β2-MG test?
May 16, 2023
Source: Cainiu Health
Dr. Yang Shuwen
Introduction
β2-MG refers to the serum β2-microglobulin test. β2-microglobulin is a β light chain of the human leukocyte antigen (HLA) molecule, and all nucleated cells in the body can synthesize β2-microglobulin. The daily production of β2-microglobulin in the body remains relatively constant. Measuring β2-microglobulin levels in blood and urine can help doctors diagnose certain diseases.
β2-MG refers to the serum β2-microglobulin test, with the specific analysis as follows:
β2-microglobulin is a β light chain of the human leukocyte antigen molecule. All nucleated cells in the body can synthesize β2-microglobulin, which then attaches to cell surfaces. The daily production of β2-microglobulin in the body remains relatively constant. Measuring β2-microglobulin levels in blood and urine helps physicians diagnose diseases such as acute or chronic nephritis, renal failure, and malignant tumors. The normal range for serum β2-microglobulin is 2.14 mg/L to 4.06 mg/L, while the normal range for plasma β2-microglobulin is 0.8 mg/L to 2.4 mg/L.
Prior to the serum β2-microglobulin test, it is not recommended to consume excessive fatty foods or large amounts of alcohol. Additionally, fasting for at least 8 hours before the test is required to prevent food from affecting the final results. If abnormal results are detected, further related examinations are necessary, followed by targeted treatment under a physician's guidance.
