Do you need to restart isotretinoin after relapse following discontinuation?
May 29, 2023
Source: Cainiu Health
Dr. Liu Wan
Introduction
After discontinuation of isotretinoin, if relapse occurs, the medication may be restarted under medical supervision. It is recommended to maintain a light diet in daily life and avoid spicy and irritating foods such as chili peppers, ginger, and garlic. Instead, consume more fresh vegetables and fruits. Additionally, it is important to maintain cleanliness and hygiene of the affected area and perform proper local care.
Isotretinoin can be restarted under medical guidance if acne relapses after discontinuation. Specific analysis is as follows:
Isotretinoin inhibits sebaceous gland activity, reduces keratinization of epithelial cells, and suppresses the growth and proliferation of Cutibacterium acnes. It is generally used for severe, treatment-resistant nodular acne. If acne recurs after stopping the medication, it may be due to factors such as improper diet or high mental stress leading to endocrine disorders, which cause abnormal sebaceous gland secretion and thus trigger a relapse. In such cases, patients may continue taking this medication to effectively alleviate symptoms. Alternatively, under a doctor's guidance, topical treatments such as erythromycin ointment or fusidic acid cream may be used; these have anti-inflammatory properties and can help relieve symptoms after recurrence.
It is recommended that in daily life, individuals maintain a light diet, avoiding spicy and irritating foods such as chili peppers, ginger, and garlic, and consume more fresh vegetables and fruits. Additionally, maintaining local cleanliness and hygiene and properly caring for the affected area are important. If any discomfort occurs, prompt medical evaluation and timely treatment are advised to prevent disease progression.
