What are the drugs that are PCSK9 inhibitors?

Jun 05, 2023 Source: Cainiu Health
Dr. Qi Zhirong
Introduction
PCSK9 inhibitors are a new class of lipid-lowering drugs, among which the more common ones are evolocumab injection and alirocumab injection. A detailed analysis is as follows: Evolocumab injection is a lipid-lowering drug whose active ingredient is human monoclonal immunoglobulin G2. The drug appears as a sterile, colorless to pale yellow, clear liquid.

PCSK9 inhibitors are a new class of lipid-lowering drugs, among which the more common ones are evolocumab injection and alirocumab injection. Specific analysis is as follows:

1. Evolocumab Injection

Evolocumab injection is a lipid-lowering medication whose active ingredient is human monoclonal immunoglobulin G2. It appears as a sterile, clear liquid ranging from colorless to pale yellow, possibly with a slight opalescence. It is commonly used in adults and adolescents aged 12 years and older with homozygous familial hypercholesterolemia, and can be used in combination with dietary therapy and other low-density lipoprotein (LDL)-lowering treatments.

2. Alirocumab Injection

Alirocumab injection is a fully human monoclonal antibody clinically indicated for the prevention of cardiovascular disease, hypercholesterolemia, and mixed dyslipidemia.

Patients should use these medications under a doctor's guidance based on their individual conditions, avoiding self-medication to prevent potential harm from inappropriate drug use. Additionally, maintaining a light diet and avoiding spicy or irritating foods is recommended in daily life.


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