What are the effects of denosumab on teeth?

Jul 27, 2023 Source: Cainiu Health

Dr. Zhang Liwen

Introduction

Denosumab is a medication used to treat osteoporosis and bone metastases. The effects of denosumab on teeth include periodontal disease, tooth displacement, and dental infections. In addition, it may also lead to conditions such as osteonecrosis of the jaw, loose teeth, and tooth loss. If you are undergoing denosumab treatment, it is recommended to have regular dental check-ups and maintain good oral hygiene practices.

Denosumab is a medication used to treat osteoporosis and bone metastases. Generally, denosumab may affect the teeth in several ways, including periodontal disease, tooth displacement, and dental infections. Specific details are as follows:

1. Periodontal disease: Denosumab may increase the risk of periodontal disease. Periodontal disease refers to inflammation and destruction of the supporting tissues around the teeth. Denosumab may interfere with the immune system's response to oral bacteria, thereby increasing the likelihood of developing periodontal disease.

2. Tooth displacement: Denosumab may cause tooth movement. This could result from changes in bone tissue and remodeling of the alveolar bone. Tooth displacement may lead to malocclusion, misaligned teeth, and other related issues.

3. Dental infections: Denosumab may increase the risk of dental infections. This may be related to its immunosuppressive effects, which reduce the body's ability to resist oral bacteria.

In addition, other potential side effects include osteonecrosis of the jaw, loose teeth, and tooth loss. If you are receiving denosumab treatment, it is recommended to undergo regular dental check-ups and maintain good oral hygiene practices. Seek prompt medical attention if any discomfort occurs to prevent adverse outcomes.

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