What is Nevus Anemicus (Bier's anemic spot), and how should it be managed?

Jul 31, 2023 Source: Cainiu Health
Dr. Zhang Heyang
Introduction
Nevus anemicus, also known as Marshall-White syndrome, is caused by autonomic nervous dysfunction and vascular vasomotor disorders. It generally does not affect daily life and therefore requires no treatment. When the arm is raised, blood from both normal and abnormal vessels flows into the heart, causing the pale patch to fade and become similar in color to the surrounding normal skin.

Marshall-White syndrome, commonly known as nevus anemicus, is caused by autonomic nervous dysfunction and vascular vasomotor disorders. It generally does not affect daily life and therefore does not require treatment. The details are as follows:

After the onset of Marshall-White syndrome, light-colored white patches often appear on the extremities. When limbs remain in a dependent position for prolonged periods, impaired vasoconstrictive regulation in some blood vessels leads to microcirculatory disturbances in the distal limbs, making the white patches more prominent. When the arm is raised, blood from both normal and abnormal vessels flows back into the heart, causing the white patches to fade and become indistinguishable from normal skin color. The patches reappear when the limb is lowered again. This condition is a congenital developmental anomaly that typically does not impact the patient's quality of life.

In summary, Marshall-White syndrome does not require specific treatment. Patients are advised to consult local physicians and manage the condition under medical guidance.


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