White spots on hands at age 50

White patches appearing on the hands at age 50 may be caused by conditions such as vitiligo, nevus anemicus, or post-inflammatory hypopigmentation, and treatment should be based on the specific underlying cause. Detailed analysis is as follows:

1. Vitiligo

This condition results from the destruction of melanocytes in the skin, leading to white patches due to a lack of melanin. It can occur on various parts of the body, including the face, back of the hands, neck, forearms, and abdomen. Treatment may include medications such as fluticasone propionate cream, halometasone lotion, or tacrolimus ointment, as recommended by a physician.

2. Nevus Anemicus

This condition is primarily related to vascular abnormalities. If blood vessels remain constricted, it can lead to abnormal pigmentation and white patches. For small lesions, topical camouflage creams may be used; if cosmetic concerns arise, medical camouflage or surgical treatment may be considered.

3. Post-inflammatory Hypopigmentation

During skin inflammation, melanocytes in the hands may be destroyed by lymphocytes or phagocytosed by histiocytes, resulting in rapid loss of pigment or impaired melanin production. As directed by a doctor, calcineurin inhibitors such as tacrolimus ointment, cyclosporine soft capsules, or pimecrolimus cream may be used.

In addition, similar symptoms may also be caused by senile leukoderma, pityriasis alba, or pityriasis versicolor. Patients are advised to visit a reputable medical facility to determine the exact cause and receive timely treatment.