What medication should be taken to reduce fever at 38.2℃?

Aug 27, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
In general, fever reduction refers to antipyresis. At 38.2°C, antipyretic medications such as ibuprofen sustained-release capsules, acetaminophen tablets, nimesulide tablets, Xiaochaihu granules, and aspirin enteric-coated tablets may be taken under medical guidance. If antipyretic drugs are needed, it is recommended to take them under the supervision of a doctor to avoid adverse effects. Ibuprofen sustained-release capsules belong to nonsteroidal anti-inflammatory drugs (NSAIDs).

In general, fever reduction refers to antipyresis. At a temperature of 38.2°C, antipyretic medications such as ibuprofen sustained-release capsules, acetaminophen tablets, nimesulide tablets, Xiao Chai Hu granules, and enteric-coated aspirin tablets may be taken under medical guidance. The details are as follows:

1. Ibuprofen Sustained-Release Capsules

Ibuprofen sustained-release capsules belong to nonsteroidal anti-inflammatory drugs (NSAIDs). They inhibit the synthesis of prostaglandins, thereby producing analgesic, anti-inflammatory, and antipyretic effects.

2. Acetaminophen Tablets

Acetaminophen tablets belong to the class of acetanilide drugs and have antipyretic and analgesic effects. By inhibiting central prostaglandin synthetase, they reduce the synthesis and release of prostaglandin PGE1, dilate peripheral blood vessels, promote sweating and heat dissipation, thus achieving antipyretic effects.

3. Nimesulide Tablets

Nimesulide tablets are a commonly used NSAID in clinical practice, possessing antipyretic, analgesic, and anti-inflammatory properties. After administration, the drug inhibits prostaglandin synthesis in the body and rapidly produces an antipyretic effect.

4. Xiao Chai Hu Granules

Xiao Chai Hu granules are primarily composed of Bupleurum, Scutellaria, processed Pinellia, Codonopsis, ginger,甘草 (licorice), jujube, and other ingredients. This traditional Chinese medicine formulation has dual effects on both exterior and interior syndromes. By promoting diaphoresis to resolve exterior patterns and clearing internal heat, it helps alleviate symptoms such as headache and fever caused by exogenous infections, thus exerting certain antipyretic effects.

5. Enteric-Coated Aspirin Tablets

Enteric-coated aspirin tablets have some antipyretic effects and can reduce fever, but high doses are usually required for significant results, and they carry a risk of serious adverse reactions. Therefore, aspirin is not typically used clinically as a standalone antipyretic agent.

If antipyretic medication is needed, it is recommended to take it under the guidance of a physician to avoid adverse outcomes.

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