Reference range for 24-hour urine microalbumin

Feb 27, 2023 Source: Cainiu Health
Dr. Zhao Xinju
Introduction
The reference range for 24-hour urinary microalbumin is generally 15–25 mg/L. A 24-hour urinary microalbumin level exceeding 30 mg/L is considered positive for microalbuminuria. However, kidney damage is more commonly assessed using the 24-hour urine protein quantification or the ratio of urinary microalbumin to creatinine at a single time point.

The reference range for 24-hour urinary microalbumin is generally 15–25 mg/L.

When 24-hour urinary microalbumin exceeds 30 mg/L, it is considered positive for microalbuminuria. However, kidney damage is more commonly assessed using the 24-hour urine protein quantification or the ratio of urinary microalbumin to creatinine at a single time point. Elevated urinary microalbumin levels or an increased microalbumin-to-creatinine ratio, indicating increased albumin excretion, suggest kidney damage. This elevation in urinary microalbumin is often observed in the early stages of diabetic nephropathy or hypertensive kidney injury.

In other kidney diseases such as diabetic nephropathy and chronic glomerulonephritis, urinary microalbumin levels also increase when proteinuria develops. It is important to identify the underlying cause of elevated urinary microalbumin and provide targeted treatment based on the primary disease. For diabetic nephropathy causing elevated microalbumin, early and adequate use of RAAS blockers (ACE inhibitors or ARBs), blood pressure control, and reduction of urinary microalbumin are recommended.

In addition, limiting protein intake, quitting smoking and alcohol, controlling blood glucose and blood pressure, and protecting kidney function can effectively manage elevated urinary microalbumin. If abnormal test results are found, please consult a doctor promptly.


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