Is taking vitamin C effective for chronic urticaria?

In general, taking vitamin C can be effective for chronic urticaria. Patients with chronic urticaria may take vitamin C in moderation as an adjunctive treatment, but long-term use is not recommended to avoid adverse effects. The detailed analysis is as follows:

Chronic urticaria refers to transient inflammatory congestion and tissue edema of the skin, mucous membranes, and blood vessels caused by various factors. Vitamin C is a water-soluble vitamin that helps maintain cellular integrity and reduces permeability of the skin and mucous membranes; therefore, it can be used as an adjunctive therapy for patients with chronic urticaria. For patients with severe conditions, vitamin C tablets can be taken orally or administered intravenously. For patients with milder symptoms, consuming more green leafy vegetables in daily life can provide sufficient vitamin C. It should be noted that chronic urticaria patients should not take vitamin C for prolonged periods. Long-term use may lead to excessive accumulation of vitamin C in the body, potentially causing adverse reactions such as mucocutaneous bleeding and urate deposition, which could worsen the condition. Therefore, long-term supplementation with vitamin C is not recommended.

Patients with chronic urticaria should use medications only under the guidance of a physician and must not self-medicate, to avoid adverse reactions.