Is it necessary to administer glucose before giving albumin?

In general, it is not necessary to administer glucose before infusing albumin. The detailed explanation is as follows:

Albumin refers to human serum albumin, which effectively increases plasma osmotic pressure and thereby helps detoxify the body. When human serum albumin is administered intravenously, the medication enters the infusion tubing. To prevent contact between albumin and other drugs—which could cause adverse reactions—and to minimize albumin waste, the line may be flushed with normal saline, glucose solution, or similar fluids before and after albumin infusion. Glucose is not mandatory; alternatives such as normal saline or nutritional solutions are also acceptable. Therefore, there is no absolute requirement to administer glucose prior to albumin infusion.

During albumin infusion, patients should avoid strenuous physical activity to prevent bleeding complications. Patients with hypertension, severe anemia, or renal insufficiency should not receive albumin, as it may pose life-threatening risks. If any discomfort occurs, patients should seek medical attention promptly and undergo standardized treatment under a physician's guidance, which will aid in their recovery.