What happens if 200ml of metronidazole is infused at once?
Under normal circumstances, metronidazole refers to metronidazole injection. Receiving a single infusion of 200 ml of metronidazole injection may cause physical discomfort and constitutes a severe overdose. The detailed analysis is as follows:
Metronidazole injection commonly causes adverse reactions during infusion, occurring in approximately 15%–30% of patients. The most frequent side effects involve the gastrointestinal system, including nausea, vomiting, loss of appetite, and abdominal pain. These symptoms are usually mild and do not require discontinuation of the drug. Neurological and psychiatric symptoms may also occur, such as dizziness, headache, limb numbness, or even optic neuritis. A single 200 ml dose is relatively high and could potentially lead to seizures. Some patients may develop allergic rashes, including skin redness, itching, or urticaria. Urinary system symptoms such as urinary tract infections or difficulty urinating, as well as decreased white blood cell count, may also occur. Most of these adverse effects are reversible and typically resolve spontaneously after discontinuation of the medication.
Patients must strictly follow medical instructions when using medications and should never self-medicate blindly, to avoid adverse effects on health. If any discomfort occurs, patients are advised to seek timely medical treatment.