Are there any side effects of long-term consumption of natto?

Nattokinase for weight loss may be effective for some people, but not for others. Nattokinase is an alkaline serine protease that can promote fat breakdown and accelerate metabolism. For individuals with relatively slow metabolism or those prone to fat accumulation, nattokinase may have a positive effect on weight loss.

In general, it is recommended to take a break after 1–2 months of consuming nattokinase. Nattokinase is an alkaline serine protease secreted by Bacillus subtilis, featuring a long half-life, high specificity, minimal side effects, and the ability to be taken orally. Nattokinase is merely a health supplement; its effects are supportive only, and health supplements should not replace medications.

Nattokinase is a protease extracted from natto, a traditional Japanese fermented food, and is produced through fermentation by Bacillus subtilis. Its core function is to dissolve blood clots, effectively improving blood circulation by breaking down fibrin, and it is often referred to as a natural anticoagulant. Due to its natural food origin and high safety profile, it is commonly used as a dietary supplement for the adjunctive prevention and treatment of cardiovascular and cerebrovascular diseases.

Nattokinase typically has antioxidant and anti-aging properties, enhances immunity, regulates blood pressure, possesses anti-inflammatory effects, and dissolves blood clots. Nattokinase exhibits antioxidant activity, which can neutralize free radicals in the body, reduce oxidative stress-induced cellular damage, and help protect cellular health. By scavenging free radicals, nattokinase may also delay the aging process.

Under normal circumstances, natto offers various health benefits such as promoting cardiovascular health, improving intestinal function and relieving constipation, regulating blood glucose levels, enhancing bone density, and boosting immunity. Nattokinase, an enzyme found in natto, has thrombolytic and anti-inflammatory effects, capable of breaking down fibrin in blood vessels and reducing the formation of blood clots. It should be noted that excessive consumption of natto may lead to indigestion or allergic reactions; therefore, moderate intake is recommended.

In general, whether healthy individuals need to take nattokinase depends on their personal health conditions. It is recommended to seek medical advice promptly and receive appropriate treatment under the guidance of a physician. While taking nattokinase, maintain a balanced diet, avoid excessive greasy foods, and engage in moderate exercise to promote blood circulation and enhance the body's natural metabolic capacity.