Can family members donate blood to each other?

Sep 20, 2024 Source: Cainiu Health
Dr. Liu Feng
Introduction
Between direct relatives, such as parents and children, blood transfusion is not recommended even if their blood types match, due to their genetic relationship. This is because blood transfusion between close relatives may trigger graft-versus-host disease, a severe transfusion complication. Although its incidence is low, once it occurs, the mortality rate is extremely high and it is almost impossible to save the patient.

Generally, direct blood transfusion between family members is not recommended.

Between close relatives, such as parents and children, even if their blood types match, mutual blood transfusion is still not advised due to their genetic relationship. This is because blood transfusion between close relatives may trigger graft-versus-host disease (GVHD), a severe transfusion complication. Although the incidence rate is low, once it occurs, the mortality rate is extremely high and often fatal. The mechanism behind GVHD involves the recipient's immune system recognizing lymphocytes in the donor's blood as "foreign" cells and launching an attack against them, leading to damage of the recipient's tissues and organs.

Patients requiring blood transfusions should follow the principle of receiving the same blood type and receive professional medical treatment and care at qualified healthcare facilities. Additionally, they should maintain emotional stability, avoid excessive tension or anxiety, eat a balanced diet, enhance nutrition, and strengthen their body's resistance.

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