What does a positive HBeAb mean, and what should be done?
Under normal circumstances, a positive HBeAb result refers to the presence of hepatitis B virus e antibody (HBeAb). A positive HBeAb test may be related to specimen contamination or testing errors, immune response following vaccination, past hepatitis B virus infection with spontaneous recovery, acute hepatitis B, or chronic hepatitis B. It is recommended to seek medical attention promptly and, under the guidance of a physician, undergo appropriate management such as general supportive care or medication therapy. Specific causes are analyzed as follows:
1. Specimen contamination or testing error
During testing for hepatitis B virus e antibody, if the specimen is contaminated or procedural errors occur, a false-positive result may arise. In such cases, re-collecting the specimen and repeating the test under accurate and reliable conditions can help confirm whether the result is truly positive.
2. Immune response after vaccination
After receiving the hepatitis B vaccine, the body produces antibodies against the hepatitis B virus, including the hepatitis B e antibody. This is one of the indicators of successful vaccination, suggesting that an immune barrier against the hepatitis B virus has been established. Usually, no special treatment is required, but it is important to ensure the completeness and effectiveness of the vaccination series.
3. Past hepatitis B virus infection with spontaneous recovery
Following a previous hepatitis B virus infection, some individuals successfully clear the virus through their own immune system. In such cases, the hepatitis B e antibody may remain positive. This represents a natural immune response, indicating that the body has developed certain immunity against the virus. Typically, there are no obvious symptoms, and regular follow-up testing is recommended to monitor viral status.
4. Acute hepatitis B
When the hepatitis B virus initially infects the body, it may trigger an acute hepatitis reaction, leading to liver inflammation and hepatocyte damage. Symptoms often include jaundice, nausea, and abdominal pain. Treatment should follow medical advice and may include medications such as entecavir dispersible tablets, tenofovir alafenamide fumarate tablets, and compound methionine choline tablets.
5. Chronic hepatitis B
Chronic hepatitis B occurs when the hepatitis B virus persists and replicates in the body after infection, causing long-term liver inflammation. Common symptoms include fatigue, decreased appetite, and liver area pain. Under medical supervision, treatment may involve medications such as diammonium glycyrrhizinate capsules, lamivudine tablets, and compound glycyrrhizin tablets.
In daily life, maintaining healthy habits, consuming adequate protein and vitamins, and reducing alcohol intake can contribute to overall health.