Can high prolactin levels cause infertility?
In general, prolactin refers to the hormone that stimulates milk production. Elevated prolactin levels may lead to infertility. The specific analysis is as follows:
Prolactin is a protein hormone secreted by acidophilic cells in the anterior pituitary gland. When prolactin levels are too high, it can negatively affect the reproductive system in multiple ways. First, elevated prolactin suppresses the synthesis and release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, thereby disrupting the secretion of pituitary gonadotropins. This leads to reduced secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), impairing ovarian function and resulting in poor follicular development and ovulatory disorders. Without normal ovulation, the likelihood of conception naturally decreases. Second, high prolactin levels may interfere with the synthesis of estrogen and progesterone. Reduced estrogen levels impair endometrial growth, making it less favorable for embryo implantation. Insufficient progesterone secretion may lead to luteal phase deficiency, increasing the risk of early miscarriage. Additionally, hyperprolactinemia may be accompanied by menstrual irregularities such as oligomenorrhea or amenorrhea, further complicating conception.
It is advisable to reduce intake of foods that may stimulate prolactin secretion, such as dairy products and soy-based foods. Maintaining a balanced diet rich in fresh vegetables and fruits is recommended to help stabilize endocrine function.