What causes lupus erythematosus?
Nov 13, 2024
Source: Cainiu Health
Dr. Yang Tiesheng
Introduction
In general, lupus erythematosus may be caused by factors such as ultraviolet radiation, exposure to chemical substances, improper use of medications, hepatitis C virus infection, or autoimmune thyroiditis. It is recommended to seek medical attention promptly, identify the underlying cause, and receive symptomatic treatment under the guidance of a qualified physician. Daily skin hygiene should be maintained, appropriate sun protection measures should be taken, and consumption of photosensitizing foods such as celery, parsley, and mushrooms should be avoided.
Systemic lupus erythematosus (SLE) is typically caused by factors such as ultraviolet (UV) radiation, exposure to chemical substances, improper use of medications, hepatitis C virus infection, or autoimmune thyroiditis. It is recommended to seek medical attention promptly, identify the underlying cause, and receive symptomatic treatment under the guidance of a qualified physician. Specific causes are analyzed as follows:
1. Ultraviolet Radiation
Prolonged exposure to UV radiation may induce apoptosis of skin epithelial cells, leading to the exposure or formation of new antigens, thereby triggering an immune response that results in SLE. It is advisable to take proper sun protection measures when going outdoors and avoid prolonged exposure to intense sunlight.
2. Exposure to Chemical Substances
Long-term contact with chemicals such as hair dyes and industrial agents may stimulate or damage the immune system, increasing the risk of developing SLE. It is important to minimize contact with chemical substances and maintain a safe, clean living and working environment.
3. Improper Medication Use
Long-term misuse of certain drugs, such as hydralazine hydrochloride tablets or procainamide hydrochloride tablets, may alter the structure of self-antigens or impair immune cell function, leading to symptoms of SLE. Patients should strictly follow medical advice when taking medications and closely monitor their physical responses, avoiding self-medication.
4. Hepatitis C Virus Infection
Hepatitis C is primarily caused by infection with the hepatitis C virus (HCV). HCV may trigger an abnormal immune response in the body, potentially leading to the development of SLE. Symptoms may include jaundice and liver area pain. Treatment under medical supervision may include reduced glutathione for injection, diammonium glycyrrhizinate injection, and ribavirin tablets.
5. Autoimmune Thyroiditis
Autoimmune thyroiditis is commonly associated with genetic predisposition and immune regulation abnormalities. This condition may lead to systemic immune dysfunction, thereby contributing to the onset of SLE. Symptoms often include neck pressure and difficulty breathing. Treatment may involve prednisolone acetate tablets, azathioprine tablets, or tacrolimus capsules, as prescribed by a physician.
Maintaining good skin hygiene, practicing appropriate sun protection, avoiding photosensitizing foods such as celery, parsley, and mushrooms, and adopting a low-fat, low-sugar diet can help support recovery and overall health.
