What is lithium carbonate sustained-release tablet?
Under normal circumstances, lithium carbonate sustained-release tablets belong to antimanic or mood-stabilizing medications. If discomfort occurs, it is recommended to promptly seek medical attention at a hospital and undergo standardized treatment under a doctor's guidance. Detailed explanations are as follows:
Lithium carbonate sustained-release tablets are primarily used to treat mania. They are effective in treating and preventing recurrence of bipolar affective disorder characterized by alternating manic and depressive episodes. They also help prevent recurrent depressive episodes and are used in the treatment of schizoaffective psychosis. Lithium carbonate sustained-release tablets exert their effects in the form of lithium ions. Their mechanism of action in controlling manic episodes involves inhibiting Ca2+-dependent norepinephrine and dopamine release at nerve terminals, promoting reuptake of norepinephrine by nerve cells from the synaptic cleft, increasing its metabolism and inactivation, thus reducing norepinephrine concentrations. Additionally, they promote serotonin synthesis and release, which contributes to emotional stability.
Common adverse reactions associated with lithium carbonate sustained-release tablets include dry mouth, thirst, polydipsia, polyuria, constipation, diarrhea, nausea, vomiting, and upper abdominal pain. Additionally, neurological side effects may frequently occur, such as fine hand tremors, fatigue, weakness, drowsiness, blurred vision, and hyperactive tendon reflexes. This medication is contraindicated in patients with renal insufficiency, severe heart disease, acute myocardial infarction, severe cardiovascular diseases such as ventricular premature contractions, pregnant women, lactating women, children under 12 years of age, dehydrated patients, patients with sodium deficiency, and those on a low-sodium or sodium-free diet.
During treatment with lithium carbonate sustained-release tablets, alcohol consumption should be avoided, as well as low-sodium or sodium-free diets. It is important to drink plenty of water during hot weather or physical activity to prevent fluid loss.
