What are the differences between melanoma and melanocytic nevi?
Generally, the differences between melanoma and melanocytic nevi include variations in shape, color, symmetry, tissue structure, and symptom presentation. A detailed analysis is as follows:
1. Shape: Melanomas often have irregular shapes with unclear borders, appearing jagged or map-like. In contrast, melanocytic nevi are typically round or oval with clear, smooth borders.
2. Color: Melanomas exhibit uneven coloring, often displaying multiple shades such as black, brown, and tan within the same lesion, with possible gradual darkening or color change over time. Melanocytic nevi usually have a uniform color, most commonly a consistent black or dark brown.
3. Symmetry: Melanomas are often asymmetrical, with one half differing in appearance from the other. Melanocytic nevi are generally symmetrical.
4. Tissue Structure: Melanomas display disorganized tissue architecture, with varying sizes and uneven distribution of cell nests, frequently invading surrounding tissues. Melanocytic nevi have an organized structure, with nevus cells arranged in nests or cords, clearly demarcated from surrounding tissues.
5. Symptom Presentation: Melanomas may present symptoms such as itching, ulceration, or bleeding within a short period. Melanocytic nevi typically remain unchanged over time, although potential malignant transformation should be monitored.
When melanoma or melanocytic nevi appear on the body, it is important to closely monitor any changes and maintain regular observation and protection. If abnormalities such as gradual enlargement, itching, or ulceration occur, prompt medical consultation is recommended to ensure health and well-being.