Can a PICC line be removed if there is a thrombus?
PICC usually refers to peripherally inserted central catheter. This type of venous catheter may develop thrombosis (blood clots). If the clot is small and asymptomatic, the catheter can generally be removed. However, if the clot is large and causes obvious symptoms, removal is typically not advised. Prior to removal, doctors need to comprehensively evaluate the patient's clot condition, overall health status, and treatment requirements. If discomfort occurs, it is recommended to seek medical attention at a hospital promptly and follow the doctor's instructions for treatment. Detailed explanations are as follows:

If the clot is relatively small and has stabilized following anticoagulant therapy without signs of progression, doctors may assess that the thrombosis risk is manageable, and catheter removal can be considered. However, this should be performed under close monitoring, and alternative safe venous access must be available.
If the clot is large or has already caused symptoms such as pain and swelling, removing the catheter might dislodge fragments of the clot, increasing the risk of pulmonary embolism and local bleeding. In such cases, catheter removal is generally not recommended. Patients with coagulation disorders may also face an increased risk of bleeding with catheter removal and therefore removal is not advised.
After catheter removal, patients should keep the puncture site clean and dry, avoid lifting heavy objects or engaging in strenuous activities, to promote healing of the puncture site and prevent complications.