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What antibiotics are used for skin and soft tissue infections?

Nov 08, 2024 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Skin and soft tissue infections generally refer to infections of the skin and subcutaneous tissues, commonly caused by hemolytic streptococci and Staphylococcus aureus. Doctors usually recommend treatment with antibiotics such as penicillins, cephalosporins, macrolides, tetracyclines, and aminoglycosides. Before using antibiotics, it is advisable to perform a drug sensitivity test first to determine the most appropriate type of antibiotic.

Soft tissue infections of the skin generally refer to infections of the skin and subcutaneous tissues, commonly caused by hemolytic streptococci and Staphylococcus aureus. Doctors usually recommend treatment with antibiotics such as penicillins, cephalosporins, macrolides, tetracyclines, and aminoglycosides. A detailed explanation is as follows:

1. Penicillins: These have anti-inflammatory and bactericidal effects and are primarily used to treat skin and soft tissue infections caused by susceptible bacteria. Commonly used medications include amoxicillin capsules, ampicillin tablets, amoxicillin and potassium clavulanate tablets, oxacillin tablets, and procaine penicillin.

2. Cephalosporins: These are broad-spectrum antibacterial agents that effectively inhibit bacterial cell wall synthesis, thereby killing pathogens. Examples include cefixime granules, cefradine dispersible tablets, cefuroxime axetil tablets, cefotaxime sodium, ceftazidime, ceftriaxone sodium, and cephalexin capsules.

3. Macrolides: These exhibit strong antibacterial activity against Gram-positive bacteria and also have certain anti-inflammatory effects. Common medications include roxithromycin capsules, clarithromycin sustained-release tablets, erythromycin enteric-coated tablets, azithromycin, josamycin tablets, midecamycin, acetylspiramycin tablets, and kitasamycin tablets.

4. Tetracyclines: These are bacteriostatic agents that achieve antibacterial effects by interfering with bacterial protein synthesis. Commonly used drugs include doxycycline hyclate tablets, oxytetracycline tablets, minocycline hydrochloride tablets, and semi-synthetic tetracyclines such as doxycycline hyclate tablets and methacycline hydrochloride tablets.

5. Aminoglycosides: These are suitable for infections caused by Gram-negative bacilli. Common medications include streptomycin sulfate, neomycin sulfate tablets, kanamycin monosulfate, and gentamicin sulfate tablets.

Before using antibiotics, it is recommended to perform a drug sensitivity test first to determine the most suitable type of antibiotic. At the same time, it is essential to use medications as directed by a physician and follow the dosage and administration instructions provided in the drug's说明书 (package insert).

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