What is the difference between adenomyoma and uterine fibroids?
Adenomyoma usually refers to uterine adenomyosis. Generally speaking, the main differences between uterine adenomyosis and uterine fibroids include pathogenesis, clinical symptoms, imaging examinations, microscopic features, treatment, and recurrence. If discomfort occurs, timely medical consultation and examination are recommended. Detailed analysis is as follows:
1. Pathogenesis
Uterine fibroids are formed by abnormal proliferation of uterine smooth muscle cells into masses, usually with clear boundaries, clearly demarcated from surrounding uterine muscle tissue. Fibroids can be single or multiple, varying in size. Uterine adenomyoma results from the invasion of endometrial glands and stroma into the uterine muscular layer, presenting as diffuse or focal hyperplasia of endometrial glands and stroma within the uterine muscle layer. There is no clear boundary, and it fuses with the normal muscular tissue.
2. Clinical Symptoms
Most patients with uterine fibroids do not exhibit clinical symptoms. Only intramural fibroids protruding into the uterine cavity and submucosal fibroids commonly cause increased menstrual bleeding and prolonged menstrual periods, but dysmenorrhea is rarely associated. Some patients may experience symptoms such as abdominal pressure, frequent urination, constipation, and back pain. The main symptom of uterine adenomyoma is secondary progressive worsening dysmenorrhea, often accompanied by menorrhagia and prolonged menstrual periods. It also may cause pelvic pain, discomfort during sexual intercourse, and infertility.
3. Imaging Examination
On ultrasound, uterine fibroids appear as round or oval masses within the uterus with clear edges. Uterine adenomyoma appears on imaging as a uniformly enlarged uterus with heterogeneous myometrial echotexture, possibly accompanied by focal hypoechoic areas.
4. Microscopic Features
Under microscopic examination, uterine fibroids are mainly composed of spindle-shaped smooth muscle cells and varying amounts of fibrous connective tissue arranged in a whorled pattern. Under microscopic examination, uterine adenomyoma is characterized by ectopic endometrial glands and stroma distributed in island-like patterns within the muscular layer.
5. Treatment and Recurrence
Treatment options for uterine fibroids include observation, medication, interventional therapy, and surgery, depending on the size, location, and symptoms of the fibroid. Treatment for uterine adenomyoma is usually more complex; medication can relieve symptoms but cannot provide a radical cure. For severe adenomyoma, surgical treatment such as local adenomyoma resection or hysterectomy may be required, but the risk of recurrence after surgery is relatively high.
Therefore, when related symptoms occur, timely medical consultation with a specialist is necessary to obtain an accurate diagnosis and appropriate treatment recommendations.