What are the functions and benefits of Motilium?

Generally speaking, Motilium refers to Domperidone tablets, a commonly used gastrointestinal motility drug, whose functions and effects include promoting gastric motility, relieving dyspepsia symptoms, assisting in the treatment of specific conditions, promoting lactation, and having a sedative effect. The details are as follows:

1. Promoting Gastric Motility

Domperidone tablets can stimulate gastric wall cells to release acetylcholine. As a neurotransmitter, acetylcholine activates smooth muscle cells within the gastric wall by binding to cholinergic receptors on the stomach lining, causing them to contract. This contraction pushes food toward the small intestine, thereby accelerating gastric emptying and enhancing gastric motility.

2. Relieving Dyspepsia Symptoms

Dyspepsia is often accompanied by weakened gastric motility and delayed gastric emptying. Domperidone tablets promote gastric motility and accelerate the digestion and emptying of food, thereby reducing the time food remains in the stomach and alleviating symptoms of dyspepsia such as abdominal distension, abdominal pain, belching, nausea, and vomiting.

3. Assisting in the Treatment of Specific Conditions

Domperidone tablets can be used to treat delayed gastric emptying caused by diseases such as diabetes and chronic gastritis. They are also effective in treating nausea and vomiting caused by migraines, radiotherapy, or chemotherapy. By enhancing intestinal peristalsis and emptying capacity, Domperidone helps alleviate symptoms associated with these conditions.

4. Promoting Lactation

In certain situations, such as insufficient lactation after childbirth, Domperidone tablets may be used short-term to promote postpartum lactation by increasing serum prolactin levels, thus enhancing milk secretion. However, long-term use or misuse of Domperidone may cause abnormally elevated prolactin levels, leading to problems such as galactorrhea, gynecomastia, and menstrual disorders.

5. Sedative Effect

Domperidone tablets may have a mild sedative effect that helps relieve anxiety and tension. However, this effect is relatively weak and not its primary therapeutic purpose.

Pregnant women, nursing mothers, and patients with hepatic or renal insufficiency should consult a physician before using Domperidone tablets. Domperidone tablets are contraindicated in children under 18 years of age. After administration, possible adverse effects should be closely monitored, and the medication should be discontinued promptly and a physician consulted if necessary.