What causes the feeling of waking up in the middle of the night with nausea and discomfort?

Generally, waking up in the middle of the night with nausea, a desire to vomit, and discomfort may be caused by improper diet, cold exposure, peptic ulcer, chronic gastritis, cholecystitis, and other conditions. Treatment may involve dietary adjustments, keeping warm, and following medical advice regarding medication. Prompt medical attention is recommended, and treatment should follow medical guidance. Detailed explanations are as follows:

1. Improper diet: Eating excessive amounts for dinner or consuming irritating foods such as greasy, spicy, or cold items may lead to indigestion, causing nausea and vomiting. Consuming spoiled or unclean food may also result in food poisoning with symptoms such as nausea and vomiting. Patients should adjust their diet, avoid excessive intake of greasy, spicy, or cold foods at night, and choose bland and easily digestible meals.

2. Cold exposure: Failure to keep the abdomen and stomach warm during sleep may cause gastrointestinal irritation, leading to symptoms such as nausea and vomiting. Patients should ensure adequate warmth for the abdomen and stomach during sleep to avoid cold exposure.

3. Peptic ulcer: Peptic ulcer is a common digestive system disease characterized by symptoms such as abdominal pain, diarrhea, nausea, and vomiting. Some patients may experience abdominal pain and nausea at night. Under a doctor's guidance, patients can take medications such as pantoprazole sodium enteric-coated capsules, domperidone tablets, and hydrotalcite chewable tablets to suppress acid production, promote digestion, and provide antacid effects.

4. Chronic gastritis: Chronic gastritis refers to chronic inflammatory changes in the gastric mucosa, resulting in mucosal congestion and erosion. Increased gastric acid secretion at night may irritate the damaged gastric mucosa, causing nausea and vomiting, often accompanied by stomach pain. Under medical guidance, patients can take medications such as pantoprazole sodium enteric-coated tablets, omeprazole enteric-coated capsules, and mosapride citrate tablets to suppress acid production and enhance gastric motility.

5. Cholecystitis: Cholecystitis is caused by inflammatory changes in the gallbladder, resulting in gallbladder wall congestion and thickening. At night, bile secretion decreases, gallbladder contraction weakens, and bile accumulates in the gallbladder, causing nausea and vomiting, often accompanied by bloating. Under medical guidance, patients can use medications such as pethidine hydrochloride tablets, diclofenac sodium enteric-coated tablets, and etapenem sodium for injection to relieve pain and exert antibacterial effects.

Patients should learn to relieve stress and maintain a pleasant mood in daily life. They can try relaxation techniques such as deep breathing and meditation to relax the body and mind.