What is the normal value of alanine aminotransferase (ALT)?

Dec 30, 2024 Source: Cainiu Health

Dr. Gao Jun

Introduction

Under normal circumstances, the normal range of alanine aminotransferase (ALT) is 0-40 U/L. Alanine aminotransferase is an important and sensitive indicator in liver function tests and is primarily present within liver cells. When liver cells are damaged, the permeability of the liver cell membrane increases, causing alanine aminotransferase to be released into the bloodstream, which may lead to an elevation in the concentration of alanine aminotransferase in the serum.

　　Under normal circumstances, the normal range for alanine aminotransferase (ALT) is 0-40 U/L. The detailed analysis is as follows:

　　Alanine aminotransferase is an important and sensitive indicator in liver function tests, primarily found within liver cells. When liver cells are damaged, the permeability of the liver cell membrane increases, causing alanine aminotransferase to be released into the bloodstream, which may lead to elevated serum levels of alanine aminotransferase. Therefore, measuring alanine aminotransferase is widely used to assess the health of liver function. Elevated levels of alanine aminotransferase may indicate the presence of liver diseases such as viral hepatitis, alcoholic liver disease, drug-induced liver injury, etc.

　　Maintaining healthy lifestyle habits is important, including adequate sleep, regular meals, and moderate exercise. Avoid long-term late nights, excessive fatigue, and excessive alcohol consumption, as these unhealthy habits can damage the liver.

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What does an elevated alanine transaminase (ALT) level indicate?

In general, an elevated level of alanine aminotransferase (ALT) refers to a test result higher than the normal range in the blood. ALT is a commonly used clinical indicator for evaluating liver cell function. It primarily exists in the cytoplasm of liver cells and is an enzyme involved in amino acid metabolism within the body. Strenuous exercise, long-term sleep deprivation, excessive alcohol consumption, and other factors may potentially cause a temporary increase in ALT levels.

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Is fasting required for liver function tests?

In general, liver function tests usually require fasting. Liver function is assessed by indicators such as alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), and cholinesterase, which help determine whether liver damage exists and its severity. Therefore, to ensure accurate test results, it is essential to strictly follow the doctor's instructions.

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What does it mean when transaminase and alanine transaminase levels are high?

In general, elevated levels of transaminase and alanine aminotransferase (ALT) may be caused by strenuous exercise, alcohol consumption, fatty liver disease, viral hepatitis, drug-induced liver injury, or other factors. If you experience any discomfort, it is recommended to seek medical attention promptly. Maintain a healthy and balanced diet in daily life, avoid high-fat and high-calorie foods, and increase the intake of dietary fiber and vitamins.

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What are transaminases?

Under normal circumstances, transaminases refer to a class of enzymes that catalyze the transfer of amino groups between amino acids and keto acids. They are widely present in animals, plant tissues, and microorganisms. Transaminases are found in high concentrations in animal tissues such as the myocardium, brain, liver, kidney, and also in mung bean sprouts. There are many types of transaminases, which can be categorized into several types including aspartate transaminase and alanine transaminase.