Can niacinamide tablets reduce melanin?
Jan 09, 2025
Source: Cainiu Health
Dr. Chen Lu
Introduction
Under normal circumstances, niacinamide tablets can reduce melanin, but the effectiveness varies from person to person. They should be used only under the guidance of a doctor. Niacinamide tablets have the ability to inhibit tyrosinase activity. Tyrosinase is one of the key enzymes in melanin synthesis, as it catalyzes the conversion of tyrosine into dopa, and subsequently into melanin. By inhibiting tyrosinase activity, niacinamide reduces melanin production.
Under normal circumstances, niacinamide tablets can reduce melanin, but the effectiveness varies from person to person. If usage is needed, it should be done under a doctor's guidance. Detailed explanations are as follows:
Niacinamide tablets can inhibit the activity of tyrosinase. Tyrosinase is one of the key enzymes involved in melanin synthesis, as it catalyzes the conversion of tyrosine into dopa, which subsequently forms melanin. By inhibiting tyrosinase activity, niacinamide effectively blocks the process of melanin synthesis, thereby reducing melanin production.
In addition, niacinamide can also reduce the transfer of melanosomes from melanocytes to keratinocytes and interfere with the cellular signaling pathways between keratinocytes and melanocytes. This mechanism further decreases melanin deposition in the epidermal layer, resulting in a fairer skin appearance.
In daily life, proper sun protection measures should be taken, such as applying sunscreen, wearing sun hats, and using umbrellas, to reduce skin damage caused by ultraviolet radiation.
