How long is the shelf life of povidone-iodine?
Jan 24, 2025
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal conditions, the shelf life of unopened povidone-iodine is generally 24 months. For opened small bottles of povidone-iodine, the shelf life is approximately 7 days, while for larger bottles, it can be extended to 10 days. However, if the povidone-iodine becomes contaminated, it may become ineffective immediately. Povidone-iodine should be stored in a cool, dark, and dry place, away from high temperatures and direct sunlight. After use, the bottle cap should be tightened promptly to prevent iodine evaporation.
Under normal circumstances, unopened povidone-iodine typically has a shelf life of 24 months. Once opened, small bottles of povidone-iodine generally remain effective for about 7 days, while larger bottles may remain effective for up to 10 days. However, if the povidone-iodine becomes contaminated, it may become immediately ineffective. Detailed explanations are as follows:
Unopened povidone-iodine typically has a shelf life of 24 months under normal conditions. This is because povidone-iodine maintains relatively stable chemical properties in a suitable environment and can effectively preserve its disinfecting and bactericidal capabilities. However, the shelf life may vary slightly depending on the manufacturer, so it is important to refer to the specific instructions provided on the product label.
Once opened, small bottles of povidone-iodine usually have a shortened shelf life of approximately 7 days. This is because opened povidone-iodine is more susceptible to external environmental factors, such as microorganisms and dust in the air, which may gradually reduce its disinfecting effectiveness. Larger bottles of povidone-iodine generally have a longer shelf life after opening, extending to about 10 days.
However, regardless of bottle size, if the povidone-iodine becomes contaminated during use—for example, by reinserting a used cotton ball or swab into the bottle—it may become contaminated with bacteria or other microorganisms and immediately become ineffective. Therefore, it is essential to maintain cleanliness and sterility when using povidone-iodine.
Povidone-iodine should be stored in a cool, dark, dry place, away from high temperatures and direct sunlight. The bottle cap should be tightly closed immediately after use to prevent iodine evaporation. Before use, inspect the povidone-iodine for color and appearance. If any abnormalities such as precipitation, cloudiness, or darkening occur, discontinue use immediately.
