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What are the side effects of Entecavir?

Feb 14, 2025 Source: Cainiu Health
Dr. Bai Hongmei
Introduction
Under normal circumstances, common formulations of entecavir include entecavir tablets, entecavir oral solution, and entecavir granules. The use of entecavir may cause side effects such as skin reactions, gastrointestinal discomfort, muscle and joint pain, neurological symptoms, and abnormalities in liver and kidney function. It is recommended to strictly follow the doctor's instructions when taking entecavir.

Generally, entecavir is commonly available in tablet, oral solution, and granule formulations. The use of entecavir may cause side effects such as skin reactions, gastrointestinal discomfort, muscle and joint pain, neurological symptoms, and abnormalities in liver and kidney function. Detailed analysis is as follows:

1. Skin Reactions

Due to individual differences and drug sensitivity among patients, some individuals may develop symptoms such as rash and itching after using entecavir. Skin reactions typically subside gradually after discontinuation of the medication and generally do not require special treatment.

2. Gastrointestinal Discomfort

Entecavir may irritate the gastrointestinal mucosa. During the initial phase of treatment, gastrointestinal discomfort such as nausea, vomiting, bloating, abdominal pain, and indigestion may commonly occur. Therefore, it is recommended to take the medication after meals to reduce the occurrence of adverse reactions.

3. Muscle and Joint Pain

Entecavir reduces liver inflammation by inhibiting hepatitis B virus replication. Long-term use may lead to muscle damage, thereby causing muscle and joint pain that may affect the patient's daily life.

4. Neurological Symptoms

As an antiviral drug, the components of entecavir may directly act on the central nervous system in the human body, interfering with the normal transmission of neurotransmitters and affecting brain function and regulation, thus causing symptoms such as headache, dizziness, and vertigo. If a patient develops severe neurological symptoms, the drug should be discontinued immediately and medical attention sought.

5. Abnormal Liver and Kidney Function

Long-term use of entecavir may impact liver and kidney function, manifesting as elevated transaminases, increased creatinine levels, and decreased glomerular filtration rate. Therefore, patients need regular follow-up tests to monitor liver and kidney function to ensure safe medication use.

It is recommended that entecavir be used strictly according to the physician's instructions to ensure safe and effective treatment. At the same time, maintaining good lifestyle habits, including balanced nutrition and appropriate exercise, can help enhance physical immunity.

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