Can patients with favism take Ganmaoling Granules?

Feb 20, 2025 Source: Cainiu Health

Dr. Bai Hongmei

Introduction

Under normal circumstances, patients with favism should not take Ganmaoling Granules, as it may worsen their condition. Favism is an inherited hemolytic disease in which patients lack the enzyme glucose-6-phosphate dehydrogenase (G6PD). This enzyme deficiency makes red blood cells more prone to rupture, leading to hemolytic anemia. Patients with favism may develop hemolytic anemia after consuming fava beans or certain medications.

Generally, patients with favism should not take Ganmaoling Granules, as it may worsen their condition. Detailed analysis is as follows:

Favism is an inherited hemolytic disease caused by a deficiency of glucose-6-phosphate dehydrogenase (G6PD) in the body. The lack of this enzyme makes red blood cells prone to rupture, leading to hemolytic anemia. Patients with favism may develop hemolytic anemia after consuming fava beans or certain medications, experiencing symptoms such as dizziness, headache, nausea, and vomiting. Ganmaoling Granules are a traditional Chinese medicine composed of ingredients such as three-leaf agleaf, golden silver flower, paracetamol, and peppermint oil. They have antipyretic and analgesic effects. Paracetamol may increase oxidative stress in red blood cells, causing them to rupture and trigger a hemolytic reaction. Since the red blood cells of patients with favism are inherently unstable, taking Ganmaoling Granules may further aggravate their condition.

When patients with favism experience cold symptoms, they should avoid taking Ganmaoling Granules to prevent worsening of the condition. They should also maintain proper dietary management to keep their condition stable.

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What foods should patients with favism avoid eating?

Under normal circumstances, individuals with G6PD deficiency (favism) should avoid eating fresh broad beans, broad bean products, certain legumes, processed foods containing broad bean ingredients, and fruits with strong oxidizing properties, as these foods may trigger hemolytic reactions and affect health. In daily life, in addition to adjusting their diet to prevent hemolysis, patients with favism should also avoid contact with broad bean pollen to prevent adverse reactions caused by inhalation.

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Can patients with favism smell mint?

When individuals with favism (G6PD deficiency) themselves are not allergic to mint, and are only occasionally exposed to small amounts of mint odor—such as when passing by mint-growing areas or smelling faint mint scent from consumer products containing mint—the amount of mint odor entering the body through the respiratory tract is generally minimal. This level of exposure typically does not cause noticeable adverse effects or trigger symptoms associated with favism. Therefore, there is generally no need for excessive concern.

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Can patients with favism eat mint?

Some patients with G6PD deficiency (favism) have a relatively stable physical condition, and after consuming small amounts of mint, do not experience adverse reactions such as hemolysis. In such cases, cautious and limited consumption may be acceptable. Mint itself does not typically directly trigger favism episodes; as long as intake is well-controlled and the individual has good tolerance to mint, it generally does not cause significant health problems.

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Why Patients with Favism Should Not Self-Medicate

Patients with favism should not take medication on their own in order to avoid potential problems such as hemolytic reactions, drug interactions, misdiagnosis or mistreatment, inappropriate drug dosing, and lack of professional guidance. Patients with favism lack glucose-6-phosphate dehydrogenase (G6PD) in their bodies, which makes their red blood cells more fragile and susceptible to oxidative damage, leading to cell rupture and hemolysis.

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Can patients with favism (G6PD deficiency) take Rehmannia glutinosa (Sh熟地黄)?

Rehmannia glutinosa (prepared) has the effects of nourishing yin, enriching blood, and replenishing essence and marrow. It may help regulate weakness symptoms caused by deficiency of qi and blood or insufficiency of the liver and kidney. Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency (favism) need to pay special attention to avoiding oxidative substances in their diet and medication choices. Since prepared Rehmannia is not an oxidative herb, it generally does not cause problems when used in appropriate amounts.

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Can patients with favism drink sweet rice wine?

Some patients with mild and stable G6PD deficiency may not experience an immediate hemolytic reaction after consuming a small amount of rice wine. This is because rice wine contains relatively low levels of alcohol and does not directly contain oxidative substances that individuals with G6PD deficiency should avoid, such as components found in fava beans. However, this does not mean that all patients can safely consume rice wine.

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Can patients with favism take Cornus officinalis (Shanzhuyu)?

Under normal circumstances, patients with favism can take Cornus officinalis. Favism is a genetic disorder in which patients lack glucose-6-phosphate dehydrogenase, and consuming fava beans or certain oxidative drugs can trigger acute hemolytic anemia. However, Cornus officinalis does not belong to fava beans or oxidative drugs and can be used under a doctor's guidance.

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Can spinach and broad beans be eaten together?

Under normal circumstances, spinach and fava beans can be eaten together, but moderation is advised during consumption. Eating large quantities of spinach and fava beans simultaneously may cause indigestion, such as symptoms like abdominal bloating and diarrhea. Especially for individuals with sensitive digestive systems or those prone to gastrointestinal discomfort, the reaction might be more severe. Patients with favism should also avoid consuming spinach and fava beans together.

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