Is receiving just one dose of the nonavalent vaccine effective?

Feb 24, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
Under normal circumstances, "9-valent" refers to the 9-valent cervical cancer vaccine. Whether a single dose of the 9-valent cervical cancer vaccine is effective mainly depends on the recipient's age and specific circumstances. For females aged 9 to 14, a single dose of the vaccine may be effective. For those aged 15 and older, a single dose may not be effective. If you experience any discomfort, seek medical attention as soon as possible.

Generally speaking, "9-valent" refers to the 9-valent human papillomavirus (HPV) vaccine. Whether a single dose of the 9-valent HPV vaccine is effective mainly depends on the recipient's age and specific circumstances. For females aged 9 to 14, a single-dose vaccination may be effective; however, for those aged 15 or older, a single dose may not be effective. If any discomfort occurs, seek medical attention promptly and receive symptomatic treatment under the guidance of a qualified physician. Detailed explanations are as follows:

For females aged 9 to 14, due to their stronger immune response, a single dose of the 9-valent HPV vaccine may be considered to provide sufficient protective effects. This adjustment is based on multiple research studies showing that within this age group, a single dose can generate immune responses comparable to those achieved with a two-dose or three-dose regimen.

However, for females aged 15 or older, due to differences in the maturity and responsiveness of the immune system, three doses of the vaccine are required to achieve optimal preventive effects. After the first dose, some antibodies are produced, but their quantity is relatively low and the duration is short, thus the antiviral effect is not significant.

In daily life, females should maintain good lifestyle habits, including a balanced diet, moderate exercise, and adequate rest, to enhance their own immunity.

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