Can I take medicine immediately after eating watermelon?
Generally, it is not recommended to take medication immediately after eating watermelon. It is advised to wait for a period of time, usually around half an hour, before taking medicine. If discomfort occurs after taking medication, prompt medical attention is recommended. The analysis is as follows:

Watermelon typically does not undergo direct chemical reactions with medications that would affect drug efficacy. However, components in watermelon such as high water and fiber content may influence the absorption rate of medications. Additionally, antioxidants and other phytochemicals in watermelon might affect enzyme activity in the liver, thereby altering the metabolic rate of certain drugs. Therefore, to avoid these potential effects, it is not recommended to take medication immediately after consuming watermelon.
Watermelon is considered a cold-natured food and contains high levels of water and fiber. Eating watermelon may irritate the gastrointestinal tract, causing discomfort symptoms such as diarrhea or abdominal pain. If gastrointestinal discomfort occurs during medication, consuming watermelon might exacerbate these symptoms and hinder recovery.
During medication, besides avoiding foods that may interact adversely with the drug, it is also important to maintain a bland diet and avoid spicy, stimulating, or greasy foods such as hot pot, barbecue, and fried foods. These types of food may affect the body's absorption of medication and potentially worsen physical discomfort.