Can you drink alcohol after eating durian?

Mar 04, 2025 Source: Cainiu Health

Dr. Yu Yongchao

Introduction

Under normal circumstances, one should not consume alcohol after eating durian. Durian contains sulfur-containing substances such as hydrogen sulfide and disulfides. These components may reduce the activity of aldehyde dehydrogenase, a key enzyme in the liver responsible for metabolizing alcohol. Decreased activity of aldehyde dehydrogenase leads to slower alcohol metabolism, thereby increasing both the duration and concentration of alcohol in the body.

Generally speaking, it is not recommended to drink alcohol after consuming durian. The specific analysis is as follows:

Durian contains sulfur-containing substances such as hydrogen sulfide and disulfides. These components may reduce the activity of aldehyde dehydrogenase in the human body. Aldehyde dehydrogenase is a key enzyme in the liver responsible for metabolizing alcohol. A decrease in its activity slows down the metabolism of alcohol, thereby increasing the duration and concentration of alcohol in the body. This not only may intensify the state of intoxication but also could increase the risk of alcohol poisoning, leading to discomfort symptoms such as nausea, vomiting, excitement, loss of coordination, and even coma.

In addition, the combined effects of durian and alcohol may have other adverse impacts on health. Durian has a high sugar content, which can easily lead to elevated blood glucose levels, while alcohol consumption may cause blood sugar fluctuations. The combined effects of both may exacerbate instability in blood sugar levels. Both durian and alcohol have certain irritative effects on the gastrointestinal tract, and consuming them together might increase the gastrointestinal burden, causing symptoms such as indigestion, abdominal pain, and diarrhea. Some opinions also suggest that components in durian may interact with alcohol, leading to cardiovascular symptoms such as abnormal blood pressure and increased heart rate, thereby increasing the risk of cardiovascular diseases.

Durian contains high levels of sugar; after consumption, it is advisable to drink more water and pay close attention to any bodily changes. If any discomfort occurs, prompt measures should be taken accordingly.

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