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Which medications can lower triglycerides?

Mar 13, 2025 Source: Cainiu Health
Dr. Liu Feng
Introduction
In general, medications such as atorvastatin calcium tablets, simvastatin tablets, ezetimibe tablets, bezafibrate capsules, and fenofibrate capsules can lower triglycerides, but medication use should be guided by a physician. Atorvastatin lowers cholesterol and triglycerides by inhibiting their synthesis in the blood lipids and promoting the breakdown of components such as triglycerides.

Generally, medications such as atorvastatin calcium tablets, simvastatin tablets, ezetimibe tablets, bezafibrate capsules, and fenofibrate capsules can lower triglycerides, but medication use should follow medical advice. A detailed explanation is as follows:

1. Atorvastatin Calcium Tablets

Atorvastatin lowers cholesterol and triglycerides by inhibiting their synthesis in the blood lipids and by promoting the breakdown of triglycerides and other components.

2. Simvastatin Tablets

Simvastatin also belongs to the statin class of drugs. Its mechanism of action is similar to that of atorvastatin calcium tablets, lowering blood lipid levels by inhibiting the synthesis of cholesterol and triglycerides.

3. Ezetimibe Tablets

Ezetimibe is an intestinal cholesterol absorption inhibitor. It can be used to treat hyperlipidemia and also to lower triglyceride levels. It can be used alone or in combination with statins to enhance lipid-lowering effects.

4. Bezafibrate Capsules

Bezafibrate belongs to the fibrate class of drugs. It lowers plasma triglycerides and very low-density lipoprotein levels by activating peroxisome proliferator-activated receptor alpha (PPAR-alpha) and regulating the expression of genes related to lipoprotein metabolism.

5. Fenofibrate Capsules

Fenofibrate capsules also belong to the fibrate class of drugs. Their mechanism of action is similar to that of bezafibrate capsules. They are primarily used to treat hypertriglyceridemia or mixed hyperlipidemia characterized mainly by elevated triglyceride levels.

In daily life, intake of high-fat and high-sugar foods should be reduced, and the consumption of vegetables, fruits, whole grains, and other foods rich in dietary fiber should be increased. Additionally, portion control at dinner and avoiding overeating are recommended.

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