Can genetic testing during pregnancy planning prevent blighted ovum?

Mar 13, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, genetic testing during pregnancy planning can help prevent empty gestational sacs, and should be performed under a doctor's guidance if needed. Genetic testing can identify whether either partner has hereditary issues that might lead to chromosomal abnormalities in the embryo. A major cause of empty gestational sacs is embryonic chromosomal abnormalities, which usually occur during the division of the fertilized egg.

Generally, genetic testing during pregnancy planning can help prevent empty gestational sacs. If necessary, it should be conducted under a doctor's guidance. Detailed analysis is as follows:

Genetic testing can identify whether either or both parents carry genetic issues that might lead to chromosomal abnormalities in the embryo. A significant cause of empty gestational sacs is embryonic chromosomal abnormalities, which typically occur during the division of the fertilized egg. If the chromosomes of the fertilized egg exhibit aneuploidy or structural abnormalities, it may result in the arrest of embryonic development and subsequently lead to an empty gestational sac. Genetic testing allows early detection of these issues, enabling timely intervention under medical guidance to prevent the occurrence of an empty gestational sac.

Genetic testing can also detect other hereditary diseases or gene mutations in either parent that might affect fertility. Although these conditions or mutations do not directly cause empty gestational sacs, they may indirectly increase the risk by affecting the normal function of the reproductive system. Through genetic testing, couples can gain a more comprehensive understanding of their fertility status and adjust their pregnancy plans accordingly to reduce the risk of an empty gestational sac.

During pregnancy planning, both partners should maintain a positive mindset and approach the results of genetic testing proactively.