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What are the efficacy and function of lidocaine injection?

Mar 13, 2025 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Lidocaine injection, also known as lidocaine hydrochloride injection, generally has functions and effects such as anticonvulsant, nerve conduction block, antiarrhythmic, pain relief, and local anesthesia. However, it is not recommended for use in certain populations, such as patients allergic to local anesthetics, patients with uncontrolled epilepsy, and patients with malignant hyperthermia.

Lidocaine injection, also known as lidocaine hydrochloride injection, typically has effects and functions including anticonvulsant action, nerve conduction block, antiarrhythmic action, pain relief, and local anesthesia. The specific details are as follows:

1. Anticonvulsant: During intravenous infusion, lidocaine hydrochloride injection may demonstrate anticonvulsant effects. It can regulate the excitability of the central nervous system, alleviate muscle spasms and airway obstruction during seizures, and prevent the risk of suffocation caused by spasms.

2. Nerve Conduction Block: Lidocaine hydrochloride can block the transmission of nerve signals, achieving localized nerve blockage. It plays a certain therapeutic role in the treatment of neuropathic pain by reducing the transmission of pain signals, thereby relieving pain.

3. Antiarrhythmic: Lidocaine hydrochloride injection can promote the outward flow of potassium ions within myocardial cells, reduce the automaticity of the myocardium, thereby assisting in restoring normal heart rhythm. In the early stages of acute myocardial infarction, lidocaine hydrochloride injection can also be used to alleviate symptoms and prevent further myocardial damage.

4. Pain Relief: Lidocaine hydrochloride injection is also used to treat certain types of pain, such as angina pectoris and postherpetic neuralgia. By inhibiting nerve conduction, it reduces pain caused by myocardial ischemia or nerve damage, improving the patient's quality of life.

5. Local Anesthesia: Lidocaine hydrochloride injection can block the conduction of nerve fibers, thereby producing an anesthetic effect in a localized area. It is commonly used during surgeries, dental procedures, gastrointestinal endoscopy, or other medical procedures to reduce the patient's sensation of pain.

However, lidocaine injection is not recommended for individuals who are allergic to local anesthetics, patients with uncontrolled epilepsy, patients with malignant hyperthermia, or other similar populations.

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